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Under hypoxia, the stabilized HIF-1 is translocated into the nucleus and dimerizes with HIF-1 and, in turn, binds to a core hypoxia response element in a wide array of genes involved in a diversity of biological processes and directly transactivates glycolytic enzyme genes

Mealli C, Sabat M, Marzilli L

Possibly as a strategy to reduce cholesterol intake, LDLR expression is significantly lower in total CD8 + colorectal tumor infiltrating lymphocytes (TILs) compared to active CD8 + TILs

Structural and functional consequences of inactivation of human glutathione S-transferase P1-1 mediated by the catechol metabolite of equine estrogens, 4-hydroxyequilenin