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Important contraindications include personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2), history of pancreatitis, severe gastrointestinal disease including gastroparesis, and pregnancy or planned pregnancy (these medications should be discontinued at least 2 months before a planned pregnancy)

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By inhibiting the enzyme nicotinamide N-methyltransferase (NNMT), these capsules may help regulate fat storage and enhance energy expenditure, making them a promising option for individuals aiming to reduce body fat and maintain a healthy weight