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Taken together, the structural plasticity of a partially folded state is hypothesized to be an intrinsic property of the NTD that allows interactions with many structurally diverse binding partners 32,35 , such as coactivators of the P160 family 36 , the basal transcription factors TATA-box binding protein and transcription factor IIF 37 , and intramolecular interactions with the LBD

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As the tissue starts to soften and lift, the edges of the scar may temporarily spread before the skin smooths and evens out