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However, the researchers noted that the study had several limitations to be considered including that the meta-analysis was based on observational studies, that PNE had the potential to be misclassified due to most of the studies being based on self-reported data, and that there was high statistical heterogeneity across the studies

It is plausible that this tendency to exhale through the nose may put vapers and hookah smokers at risk for inflammation and cancers of the nose and sinuses and throat, conditions seen less often in cigarette smokers, according to the study authors

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