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Description

Common genetic variants in the GLP1R gene (e.g., rs6923761) and GIPR gene (rs1800437) correlate with differences in receptor density and signaling efficiency

Glucuronidation linked moieties (acyl, phenolic, hydroxy) predominates the diversity in substrate recognition, and all of the UGTs are capable of forming linked glucuronides, albeit with different efficiencies and turnover rates (Tukey & Strassburg, 2000)