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Computational investigation of curcumin, a natural polyphenol that inhibits the destabilization and the aggregation of human SOD1 mutant (Ala4Val)

Researchers used a chemogenetic strategy to activate PV neurons and found that this significantly improved learning speed and perceptual learning ability in Fmr1 knockout mice ( De novo protein synthesis was elevated in hippocampal PV- and somatostatin-expressing inhibitory neurons

Nature 362 , 127133 (1993)

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