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Peptides of similar size show highly variable nasal absorption depending on molecular weight, charge, and formulation excipients

For metabolic research protocols, this neutrality profile is a key reason both peptides remain under investigation despite the absence of approved therapeutic status

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In ethanol-induced gastric lesion models in rats, BPC-157 administered at doses of 10 ng/kg to 10 g/kg (intraperitoneally or intragastrically) produced dose-dependent reduction in lesion area, with some protocols reporting near-complete lesion prevention at 10 g/kg within 30 minutes of administration