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This process, coupled with the exhaustion of myeloid and lymphoid cells, synergistically induces a significant upregulation in the production of pro-inflammatory cytokines, including interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-)

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Delphinidin induces antiproliferation and apoptosis of endometrial cells by regulating cytosolic calcium levels and mitochondrial membrane potential depolarization

These studies together define regulatory networks essential for pigmentation, secondary metabolism, stress adaptation, and nutritional quality (Castrilln-Arbelez and Dlano-Frier, 2016