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Genetics, 190(4), 11571195

Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds

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As illustrated in Figure 6A and SFigure 2A , enzymes responsible for BA synthesis such as CYP7A1 , CYP8B1 , CYP7B1 and BAAT showed a significant decrease in livers of DILI patients