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Chemoprevention of lung cancer by tea

306 Exposure to arsenic can result in toxicity, primarily caused by the generation of reactive oxygen intermediates during its redox cycling and metabolic activation

Ferroptosis is a novel form of iron-dependent programmed cell death characterized by specific hallmarks, such as glutathione depletion, decreased glutathione peroxidase activity and the inability of lipid oxides to be processed through the glutathione peroxidase (GPX) pathway, which is catalyzed by GPX4

GSH Scavenging 4-Vinylpyridine was added to a buffer sample containing 1 mM GSH at 18C (final concentration 4VP is approximately 10 mM)