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Kurapatti M, Carreira D

It does not weaken the LES as caffeine does

We aimed to address the following topics in the consensus: (1) clinical manifestations of B12 deficiency (neurological and hematological endpoints), (2) risk groups, (3) causes of B12 deficiency, (4) laboratory diagnosis of B12 deficiency, and (5) treatment and long-term management of the deficiency