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Injecting the water directly onto the lyophilized powder can physically damage the peptide structure

It is not always the case, but you need to be checked to diagnose the cause.

Identification of the Lipolytic Domain of GH Pre-clinical studies identifying the C-terminal region of GH as the locus of its lipolytic activity established that peptides corresponding to positions of hGH retained significant fat-mobilising activity in adipocyte models and in vivo, while lacking the growth-promoting and insulin-antagonistic effects of full-length GH