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Delivery of oligonucleotides to the liver with GalNAc: from research to registered therapeutic drug

doi: 10.5152/tjg.2018.17297

The whole process depends on the activation of EGFR

plantarum ZLP001 counteracted to the increase in intestinal permeability induced by enterotoxigenic Escherichia coli via prevention of a decrease in the level of TJ proteins (claudin-1, occludin and ZO-1) (Wang et al., 2018)