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A multivariate study revealed a link between being female, having AD, participating in wet activities, and having CHE

As of May, the case remains undecided

Besides e-cigarettes, which work by heating a flavoured liquid mixed with nicotine to generate a vapour, industry players have also touted snus, a moist powdered tobacco, and "heat-not-burn" tobacco products as "safer" alternatives to cigarettes

Conclusion Understanding the function and mechanism of action of the various components of E-cigarette vapour in mediating human bone cell function, in addition to long term studies to determine the potential harm of chronic E-cigarette use on human bone will be important to inform users of potential risks, particularly regarding bone healing following orthopaedic surgery and injury