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These seemingly paradoxical effects may be one explanation for why patients with G6PD-d display increased susceptibility to infection indicative of an impaired immune response, while also displaying increased autoimmunity and inflammation indicative of an overactive immune system 13

Phase II Conjugation Enzymes8 Methyltransferase Detoxification Enzymes and Methylation Capacity A cells methylation capacity is defined as the ratio of S-adenosylmethionine (SAM) to S-adenosylhomocysteine (SAH)

When the peptide binds to these receptors in fat tissue, it triggers a cascade that increases lipolytic enzymes, breaking down stored triglycerides into free fatty acids for energy use