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Blood 98:590a, 2001

Autophagy enhancement and reduction of protein aggregation The accumulation of misfolded proteins, such as A and -synuclein, is a hallmark of several neurodegenerative disorders, such as AD and PD

Bacterial metabolites such as HPHPA (4-hydroxyphenylpropionic acid) and DHPPA can indicate Clostridia overgrowth, which has been associated with altered dopamine metabolism