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When levels are high or symptoms like confusion, breathing problems, or loss of consciousness appear

[Abstract]2022 Dec 13;41(11):111803

If, during the cardiovascular evaluation, the patient's medical history or electrocardiographic investigations reveal findings indicative of or consistent with coronary artery vasospasm or myocardial ischemia, dihydroergotamine mesylate nasal spray should not be administered (see CONTRAINDICATIONS)