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However, this approach is not without limitations, including glucocorticoid resistance, the occurrence of numerous adverse effects, suboptimal drug delivery, and other complicating factors that collectively necessitate the pursuit of innovative therapeutic avenues [6]

The blood goes through a machine that removes the stem cells

Moreover, risks of total mortality, cardiovascular mortality and hospitalisation were the highest in the underweight chronic heart failure patients, while risks of cardiovascular mortality and hospitalisation were the lowest in overweight patients [65]