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Natural products, derived from various sources, exhibit high safety profiles and possess the ability to interact with multiple disease targets, making them valuable resources for drug development [4]

The literature outlines hundreds of natural products that have aromatase inhibiting qualities including substances like apigenin, chrysin, or luteolin

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As a microvascular complication of diabetes, the characteristic lesions of DKD include thickening of the basement membrane of renal capillaries and vascular damage, resulting in reduced blood flow and oxygen delivery to the kidneys