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Mammalian cells are thought to maintain an appropriate pool of cytosolic iron by balancing iron uptake and storage in ferritin cages with the release of ferritin-sequestered iron through degradation of these proteinaceous cages (Arosio et al, 2009)

Through synthetic biology techniques, scientists can genetically engineer bacteria with the ability to target the delivery of neuroprotective factors (such as glucagon-like peptide-1) 487 or to interfere with disease processes by regulating the gut-brain axis

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