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The relative risk of all-cause mortality due to SLT use is also higher among women.[9] Several studies have shown that women have difficulty in quitting tobacco, tend to experience faster relapse due to stressful events or depression and fail to maintain long-term abstinence.[10,11,12] Evidence suggests that estrogen may enhance nicotine metabolism in women, which can affect their ability to quit tobacco successfully.[13] Since its introduction in the 17 th century in India, tobacco chewing was believed to have calming and stimulating qualities and was not only socially acceptable but also a part of its culture.[14] SLT use can be found in other South and Southeast Asian countries as well

The anthers of the four longer stamens are close to the opening of the corolla tube or are slightly above it

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Sometimes, jaundice can lead to an early diagnosis of cancer