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Cu ions directly bind to the lipoyl groups, inducing aberrant oligomerization of DLAT and other TCA cycle enzymes, promoting the loss of Fe-S cluster proteins

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10.1111/bcpt.13313 12 ChenX.WanJ.LiuJ.XieW.DiaoX.XuJ.et al (2010)

When interpreted with qualified provider guidance, these predispositions can clarify whether oxidative stress is a meaningful factor in your health picture and whether targeted interventions warrant consideration alongside lifestyle foundations like sleep, stress management, and antioxidant-rich nutrition