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Following xenobiotic exposure, enzyme induction and its associated hepatocellular hypertrophy are not usually immediately apparent, with a maximal response occurring a few days to a week or more after exposure, since the enzyme inducer must first reach steady state, and new drug-metabolizing enzymes need to be synthesized

10.1002/mds.26424 182 ProdoehlJ.BurciuR

Each cage had a linear feeder at the front and a nipple drinker at the back