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April 23 Product: Day One Biopharmaceuticals Ojemda Indication: Pediatric low-grade glioma The FDA has approved the first medicine for children with relapsed or refractory pediatric low-grade glioma (pLGG) with BRAF fusions or rearrangements, Day One Biopharmaceuticals announced Tuesday

Blood 88(10):67a, 1996

Celastrol attenuates cadmium-induced neuronal apoptosis via inhibiting Ca2+-CaMKII-Dependent Akt/mTOR pathway

A study published in the Proceedings of the National Academy of Sciences found that aging is associated with a 47% decrease in the catalytic subunit (GCLC) and a 52% decrease in the modulatory subunit (GCLM) of glutamate-cysteine ligase, the rate-limiting enzyme for glutathione production