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Chronic HCV infection has been associated with higher expression of 8-OHdG, an indicator of oxidative DNA damage, which may lead to carcinogenesis 83,109

Conversely, other studies report reductions in fasting glucose, mean daily glucose, and insulin requirements (130), along with attenuated inflammatory responses during the honeymoon period (the early post-diagnosis phase characterized by residual -cell function and lower insulin requirements) through decreased serum TNF- levels, thereby prolonging honeymoon duration (131)

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Samples were denatured at 95 C for 10 min and separated by 15% SDS-PAGE