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In the CAR-T field, the inclusion of the costimulatory receptor 4-1BB in the CAR architecture also boosts mitochondrial health and biogenesis, enhancing T-cell persistence and increasing therapeutic efficacy (118, 131134)

Environ Sci Pollut Res 19:39773988 van der Steen JJ, de Kraker J, Grotenhuis T (2012) Spatial and temporal variation of metal concentrations in adult honeybees (Apis mellifera L.)