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Certain individuals are at a higher risk for B12 deficiencyincluding those following strict vegan or vegetarian diets, as well as patients with conditions that impair nutrient absorption, such as pernicious anemia, celiac disease, Crohns disease, or a history of gastrointestinal surgery

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It can destroy the parietal cells, leading to dysregulation of stomach acid release as well as decreased intrinsic factor

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