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Early symptoms of MS include: Chronic fatigue Difficulty walking or loss of balance Numbness and tingling in the extremities Muscle pain, stiffness or spasms Vision problems Slowed cognition Motion sickness, nausea and vomiting Progression of Multiple Sclerosis Multiple sclerosis is a progressive disorder with four identified phases: Clinically isolated syndrome (CIS) is when MS symptoms first appear, characterized by inflammatory demyelination

These are different pharmacological endpoints citing one to support the other misrepresents what the studies actually measured

Bahmani F, Bathaie SZ, Aldavood SJ, Ghahghaei A

doi: 10.1002/iub.1590 117 IshigakiS.SobueG