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Over 60% of the total 4MSOB ITC in larval frass was found in the form of conjugates, with more than half being 4MSOB ITC-Cys (Fig

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For instance, in adrenocortical carcinoma IGF-1R inhibition with the kinase inhibitor NVP-AEW541 was found to induce compensatory activation of ERK and sustained mTOR activation, possibly via EGFR [79]