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Nanobody-based methods for in vivo cell labeling, such as the NaNuTrap, allow for early and specific labeling of cell nuclei, overcoming limitations of fluorescent protein maturation time and expanding the utility of fluorescent proteins for live imaging studies in fast or early developmental processes

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In comparison, placebo produced only 3.1% weight loss

Commonly Reported (Intranasal): Mild stinging or irritation in nasal passages (transient, resolves within minutes) Nasal dryness with repeated daily use Mild taste or odor disturbance immediately after administration Uncommonly Reported: Headache (mild, typically with higher doses) Dizziness (transient) Fatigue (paradoxical, reported rarely) Notably Absent: Sedation or drowsiness (consistently absent across clinical comparisons) Cognitive impairment or psychomotor slowing Tolerance development within standard 14-day courses Physical dependence or withdrawal symptoms upon cessation Rebound anxiety after treatment discontinuation Muscle relaxation or ataxia Serious Adverse Events: No serious adverse events have been attributed to Selank in published clinical literature