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it is, at best, a mechanistically reasonable adjunct whose independent contribution has not been quantified in controlled human trials

Adults acutely exposed to BPA show tissue accumulation, altered retinal physiology, and changes in gene expression We observed no mortality in adult zebrafish resulting from a 24 hr exposure to either 0.1 M (high) BPA, 0.001 M (low) BPA, or 0.0003% DMSO (vehicle)

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Genes involved in repair, cellular maintenance, stress resistance, and normal metabolic function may become less active, while genes associated with inflammation and dysfunction may become more active