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In SECIS elements, the conserved adenosines are contained in a simple open loop (10,15) (Figure 1)

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Handling and Storage Recommendations Store unopened vials at 28 C , with 20 C recommended for long-term storage Protect from light and moisture After reconstitution, store solutions at 28 C and use within laboratory-defined timeframes Avoid repeated freeze-thaw cycles Follow standard laboratory safety, labeling, and handling procedures All handling is performed within laboratory research environments