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The studies, led by Research Associate Yevgeniya Mironova, PhD, discovered that OPCs acutely alter the extracellular matrix as they begin to transform into oligodendrocytes, giving rise to a unique protein signature a Dandelion Clock-like Structure or DACS that surrounds each differentiating OPC

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Coffee intake and the incident risk of cognitive disorders: A dose-response meta-analysis of nine prospective cohort studies

In a mouse model of hepatocellular carcinoma, regulatory T cells (Tregs) with high IGF-1R expression presented increased PI3K/AKT/mTOR signaling and were able to produce more ATP, lactate and ROS, which contribute to enhanced immunosuppressive effects (72)