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LaVaute T, Smith S, Cooperman S et al (2001) Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

protein misfolding, mislocalization of TDP-43 to the cytoplasm, ER stress, inhibition of ER-Golgi transport, and apoptosis, in neuronal cells expressing pathological forms of TDP-43 or SOD1 (Parakh et al., 2020)