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[ 4 ] While these rural-urban disparities in tobacco use are partly associated with certain sociodemographic risk factors characteristic to rural populations like employment status, income level, and educational attainment, when these sociodemographic risk factors are controlled for during analysis, the disparities in tobacco use and associated tobacco-related burdens still remain between rural and urban populations

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In studies with evaluation for emphysema, it appears that protease levels were higher in some persons with emphysema than they were in control groups (Muley et al