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ROS can damage cellular components such as lipids, proteins, and DNA, leading to cell death and loss of cardiac contractile function

LevineMConry-CantilenaCWangYWelchRWWashkoPWDhariwalKRet al

6) may serve as sensitive readouts of antioxidant adaptation in disease-relevant models

Biogenic SeNPs are usually characterised by enhanced stability and biocompatibility, in consequence of natural biomolecules being capping agents that prevent aggregation, increase their biological activity and protect them from physicochemical degradation ( SeNPs have shown strong preclinical potential for cancer diagnosis, drug delivery and gene therapy, but their clinical translation is still in initial stage