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Reporting Adverse Events or Safety Concerns If you experience or suspect an adverse event, contamination, or quality issue with this product, report it immediately to: Hospira Pfizer: Manufacturer contact information available on the product vial FDA MedWatch: 1-888-SAFEMED (1-888-723-3633) or online at fda.gov/medwatch Poison Control: 1-800-222-1222 (for toxicology guidance) Your institutional pharmacovigilance system: If you work for a hospital, clinic, or healthcare institution Regulatory Compliance By purchasing and using this product, you agree to comply with all applicable FDA regulations, state pharmacy laws, and professional licensing requirements

Mangeot PE, Risson V, Fusil F, Marnef A, Laurent E, Blin J, Mournetas V, Massourides E, Sohier TJM, Corbin A, Aube F, Teixeira M, Pinset C, Schaeffer L, Legube G, Cosset FL, Verhoeyen E, Ohlmann T, Ricci EP (2019) Genome editing in primary cells and in vivo using viral-derived nanoblades loaded with Cas9-sgRNA ribonucleoproteins