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Conclusion Our results indicate that repeated treatment of the U87 MG cell line with a combination of 5-Fu, cisplatin, and paclitaxel induces cross-resistance, causing MDR against other chemotherapeutic agents that are distinctly different in terms of chemical structure and mechanism of action

Further investigations in several cancer types, such as gastric 64 and colorectal cancers 65 , demonstrated that curcumin has specific effects on cancer cellular processes, including the cell cycle

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To view a copy of this licence, visit About this article Cite this article Jomova, K., Raptova, R., Alomar, S.Y