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doi: 10.3390/nu11092169 550 LovsziMSzegediAZouboulisCCTrcsikD

Unlike many peptides, it holds up in acidic environments and at room temperature for short periods, which is part of why it works both as an injectable and, in some forms, orally

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Application of exogenous LOXL2 to cultured cartilage explants (derived from bovine articular cartilage) and engineered chondrogenic constructs (primary chondrocytes cultured to create a self-assembled structure), which were later implanted into athymic mice, promoted tissue maturation (increased mature crosslinks) and enhanced tensile mechanical properties (Makris et al ., 2014)