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Cell Biol 76, 102084 (2022)

For example, in work by Jiang et al, a possible negative regulation of TGF1 (transforming growth factor beta 1) by Nrf2 activation was observed, raising the question of whether Nrf2 negatively regulates TGF1 expression by direct binding to the promoter region of its gene or by other, downstream effects

Hung TH, Huang SY, Chen SF, Wu CP, Hsieh TT

Fecal excretion of total carnitine was less than 1% of the administered dose.10 After attainment of steady state following 4 days of oral administration of Levocarnitine Tablets (1980 mg q12h) or Oral Solution (2000 mg q12h) to 15 healthy male volunteers, the mean urinary excretion of levocarnitine during a single dosing interval (12h) was about 9% of the orally administered dose (uncorrected for endogenous urinary excretion)