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doi: 10.1016/j.bbabio.2008.03.005 21 OjhaRTantrayIRimalSMitraSCheshierSLuBet al

This, in turn, enhances the metabolic rate and activates a gene called SIRT1, often referred to as the longevity gene due to its role in reducing the risk of conditions such as diabetes, obesity, metabolic syndrome, atherosclerosis, kidney disease, liver disease, neurodegeneration, and cancer

A study published in The New England Journal of Medicine showed that male participants over 60 years old, who took hGH for six months gained on average 8.8% lean body mass and lost 14% fat mass