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In this experimental study, we conducted microarray and in-silico analyses to demonstrate and analyze the expression of metabolite interconversion enzyme genes in sperm and Sertoli cell tubules

Several pharmacological agents, such as tocilizumab and pentoxifylline, have been proposed to counteract these inflammatory-mediated fibrotic processes

Here we speculate that AT2 cells aim to increase expression of surfactants including both proteins and lipids to defense against pathogens, while abnormal surfactant transporting system may lead to surfactant deficiency finally

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