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UVA radiation can cause hair color changes by penetrating deeply into the cortex and inducing biochemical damage, whereas UVB radiation leads to protein depletion and structural damage to the cuticle.16,17 Tobacco use Smoking is associated with hair graying through increased free radical production

Acyl-coenzyme A synthetase long-chain family member 4 is involved in viral replication organelle formation and facilitates virus replication via ferroptosis

These correlations confirm that oxidative modification of bio-molecules, in this case DNA, may be one of the mechanisms of periodontal tissue destruction in the course of periodontitis