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Simultaneously, it modulates metalloproteinase activity: it stimulates MMP-2 (which remodels damaged collagen) while upregulating TIMP-1 and TIMP-2 (which prevent excessive degradation)

26 randomised trials, 1,721 people: significant improvement in skin hydration and elasticity versus placebo A second meta-analysis, 14 trials, 967 people: same direction over 4 to 12 weeks Typical protocol: daily supplementation, results measured at 8 to 12 weeks What was measured: elasticity, hydration, roughness, not excess skin Those are real results from well-designed trials, and if your goal is better skin quality, a collagen supplement is a low-risk, evidence-backed habit

Horii T, Oikawa Y, Kunisada N, Shimada A, Atsuda K