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PMID: 21224234

Its effectiveness may depend on: Dose Duration of use Product quality Baseline glutathione status Digestive and metabolic differences The outcome being measured Increasing a glutathione laboratory measurement does not automatically establish a clinical benefit, but the evidence does challenge the absolute claim that ordinary oral glutathione cannot be absorbed or used

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Thus, the development of APOL1-associated nephropathy requires the presence of a second factor (229)