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However, the increase in ROSs induced by drugs seems to play a different role compared to the role of ROS originally generated in malignant tumors

Nanoparticles were designed with a 2,2-(propane-2,2-diylbis(sulfanediyl)) bis(ethan-1-ol) linker that could be oxidized by ROS, decompose into oligomeric units, and release the ruthenium catalyst

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INTRODUCTION As one of the driving forces behind the cellular detoxification machinery, glutathione S -transferases (GSTs) and especially the pi class glutathione S -transferase P1 (GSTP1) is currently in the focus of the cancer research community, evaluating the relevance of GSTP1 epimutations for cancer development and its potential as a major epigenetic cancer biomarker