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The Core Facilities Center Cellular and Molecular Technologies in Plant Science of Komarov Botanical Institute of RAS

Adult C57BL/6 mice, aged 811 weeks, are selected for this model

While GLP-1 analogs for treatment of type 2 diabetes cause mild-to-moderate nausea and vomiting in a significant proportion of patients, their benefits in terms of weight loss and improved glycemic control have allowed the class to overcome these tolerability concerns and become one of the most-prescribed classes of type 2 diabetes medications in the US and Europe (326)