PubMed 34714971 Key Study Summaries Study 1: GHK-Cu as a Natural Modulator of Skin Regeneration Authors: Pickart L, Vasquez-Soltero JM, Margolina A Journal: BioMed Research International , 2015 Condition: Hair follicle miniaturisation and skin ageing Treatment: GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) Sample: Comprehensive review of preclinical and clinical data Key Result: GHK-Cu increased hair follicle size by up to 40% and reactivated dormant follicles from telogen to anagen phase Evidence Level: Level III (systematic review of non-randomised studies) PubMed: 26236730 Study 2: Microneedling in Androgenetic Alopecia Landmark RCT Authors: Dhurat R, Sukesh M, Avhad G, Dandale A, Pal A, Pund P Journal: International Journal of Trichology , 2013
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Hormones: Hormonal changes, such as those related to the menstrual cycle, pregnancy, or menopause, can cause anaemia, dark circles, and puffiness due to water retention
Standard dosing Dose range : 5-15mg per injection Frequency : 2-3x weekly (Monday/Thursday or Monday/Wednesday/Friday) Most common : 10mg twice weekly Conservative start : 5mg twice weekly for first 2 weeks, then increase Loading phase (optional): 10mg 3x weekly for 4 weeks, then 2x weekly maintenance Reconstitution Standard protocol : Add 2ml bacteriostatic water to 50mg vial Concentration : 25mg/ml Dose calculations : 5mg dose = 0.2ml (20 units on insulin syringe) 10mg dose = 0.4ml (40 units) 15mg dose = 0.6ml (60 units) Vial duration : 50mg vial lasts 5-10 injections depending on dose Use our reconstitution calculator for exact measurements
