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2279-C ASTHMA AND OBESITY - SYNERGISTIC EFFECTS ON HEPATIC METABOLISM IN A MOUSE MODEL Tim Westhoff 1 , Holger Garn 2 , Sarah Miethe 2 , Verena Von Blow 3 , Martin Roderfeld 3 and Elke Roeb 3 , (1)Justus-Liebig-University, (2)Philipps University, (3)Justus-Liebig-University, Giessen Background: Obesity, as a component of the metabolic syndrome, is a widespread disease with steadily increasing case numbers in industrialized countries and serious health consequences such as non-alcoholic fatty liver disease (NAFLD)

Pediatr Nephrol 9:458463 Maxwell H, Dalton RN, Nair DR, Turner C, Saunders AJ, Rigden SP, Rees L (1996) Effects of recombinant human growth hormone on renal function in children with renal transplants

The tar phase of cigarette smoke contains long-lived radicals, while the gas phase contains short-lived radicals such as nitric oxide and superoxide

Cisplatin also enters cells via passive diffusion due to its neutral charge and small size (Hromas et al., 1987