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Although there are few advantages of one antipsychotic treatment over another, when treating patients with psychosis and coexisting SUDs, the use of second-generation antipsychotics may be preferred over first-generation antipsychotics due to their better tolerability profile, including a lower liability for inducing extrapyramidal side effects [12]

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Repeated low doses of LSD in healthy adults: a placebo-controlled, dose-response study